The use of characteristic volumes to measure cavity terms in reversed phase liquid chromatography

Abstract

In the correlation of reversed-phase liquid chromatography capacity factors through the equation, {Mathematical expression} the use of McGowans characteristic volume, Vx, which can be trivially calculated, is entirely equivalent to the use of Leahy's computer-calculated intrinsic volumes, V1, for the cavity term mV/100. It is shown that for 209 gaseous, liquid, and solid solutes, the two sets of volumes are related through the equation, {Mathematical expression} with a standard deviation of only 1.24cm3 mol-1, and a correlation coefficient of 0.9988. © 1987 Friedr. Vieweg & Sohn Verlagsgesellschaft mbH.