Circular dichroism, a powerful tool for the assessment of absolute configuration of flavonoids

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Abstract

Circular dichroism is a powerful tool for establishing the absolute configuration of flavonoids and proanthocyanidin analogues. It has been utilized to study the configuration of flavanones, dihydroflavonols (3- hydroxyflavanones), flavan-3-ols, flavan-4-ols, flavan-3,4-diols, flavans, isoflavans, isoflavanones, pterocarpans, 6a-hydroxypterocarpans, rotenoids, 12a-hydroxyrotenoids, neoflavonoids, 3,4-dihydro-4-arylcoumarins, 4-arylflavan-3-ols, auronols, homoisoflavanones, proanthocyanidins, and various classes of biflavonoids. Results relevant to the correlation of circular dichroic data and the absolute configuration of the diastereoisomers of some of the above classes of compounds will be discussed. © 2005 Elsevier Ltd. All rights reserved.

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Slade, D., Ferreira, D., & Marais, J. P. J. (2005). Circular dichroism, a powerful tool for the assessment of absolute configuration of flavonoids. Phytochemistry. Elsevier Ltd. https://doi.org/10.1016/j.phytochem.2005.02.002

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