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Enantioselective, Copper(I)-Catalyzed Three-Component Reaction for the Preparation of Propargylamines

Angewandte Chemie - International Edition (2003) 42(46) 5763-5766
DOI: 10.1002/anie.200352578
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Abstract

The one-pot reaction of alkynes, aldehydes, and secondary amines in the presence of CuBr/quinap as the catalytic system provides various enantiomerically enriched propargylamines in good yields (up to 99%) and good selectivities (up to 96% ee) [Eq. (1)].

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CITATION STYLE

APA

Gommermann, N., Koradin, C., Polborn, K., & Knochel, P. (2003). Enantioselective, Copper(I)-Catalyzed Three-Component Reaction for the Preparation of Propargylamines. Angewandte Chemie - International Edition, 42(46), 5763–5766. https://doi.org/10.1002/anie.200352578

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