Abstract
The highly chemo- and enantioselective organocatalytic [C+NC+CC] coupling process between aldehydes, dialkyl 2-aminomalonates and α,β-unsaturated aldehydes is presented. The reaction gives access to highly functionalized pyrrolidine derivatives in good yields with >10:1 dr and 90-98% ee. © 2007 Elsevier Ltd. All rights reserved.
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CITATION STYLE
APA
Ibrahem, I., Rios, R., Vesely, J., & Córdova, A. (2007). Organocatalytic asymmetric multi-component [C+NC+CC] synthesis of highly functionalized pyrrolidine derivatives. Tetrahedron Letters, 48(36), 6252–6257. https://doi.org/10.1016/j.tetlet.2007.07.031
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