Cross-coupling reactions of organoboranes: An easy method for CC bonding

Abstract

The palladium-catalyzed cross-coupling reaction between different types of organoboron compounds and various organic halides or triflates in the presence of base provides a powerful and general methodology for the formation of carboncarbon bonds. The Csp2B compounds (such as aryl- and 1-alkenylboron derivatives) and Csp3B compounds (alkylboron compounds) readily cross-couple with organic electrophiles to give coupled products selectively in high yields. Recently, the CspB compounds (1-alkynylboron derivatives) have been also observed to react with organic electrophiles to produce expected cross-coupled products. The overview of some of such coupling reactions is discussed here in this article. © 2011 The Chemical Society of Japan.