The applicability of liposomes as drug carriers for the topical route of administration was investigated using triamcinolone as a model drug. The liposomal encapsulation favourably altered the drug dipposition; the concentration of the drug decreased at the site of its adverse effects and increased at the site where its activity is desired. © 1980.
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Mezei, M., & Gulasekharam, V. (1980). Liposomes - a selective drug delivery system for the topical route of administration I. Lotion dosage form. Life Sciences, 26(18), 1473–1477. https://doi.org/10.1016/0024-3205(80)90268-4