For some highly endangered species there are too few reproductively capable animals to maintain adequate genetic diversity, and extraordinary measures are necessary to prevent their extinction. Cellular reprogramming is a means to capture the genomes of individual animals as induced pluripotent stem cells (iPSCs), which may eventually facilitate reintroduction of genetic material into breeding populations. Here, we describe a method for generating iPSCs from fibroblasts of mammalian endangered species.
CITATION STYLE
Ben-Nun, I. F., Montague, S. C., Houck, M. L., Ryder, O., & Loring, J. F. (2015). Generation of induced pluripotent stem cells from mammalian endangered species. In Methods in Molecular Biology (Vol. 1330, pp. 101–109). Humana Press Inc. https://doi.org/10.1007/978-1-4939-2848-4_10
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