Quantitative Chromosome Conformation Capture (3C-qPCR)

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Abstract

Many population-based methods investigating chromatin dynamics and organization in eukaryotes are based on the chromosome conformation capture (3C) method. Here, we provide an updated version of the quantitative 3C (3C-qPCR) protocol for improved and simplified quantitative analyses of intra-chromosomal contacts.

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Rebouissou, C., Sallis, S., & Forné, T. (2022). Quantitative Chromosome Conformation Capture (3C-qPCR). In Methods in Molecular Biology (Vol. 2532, pp. 3–13). Humana Press Inc. https://doi.org/10.1007/978-1-0716-2497-5_1

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