Management of Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS)

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Abstract

A common and challenging side effect associated with CAR-T cell therapy is immune cell-associated neurotoxicity syndrome (ICANS), which occurs in 20-60% of patients, of whom 12-30% have severe (≥grade 3) symptoms.

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Rees, J. H. (2022). Management of Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS). In The EBMT/EHA CAR-T Cell Handbook (pp. 141–145). Springer International Publishing. https://doi.org/10.1007/978-3-030-94353-0_27

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