Thermosensitive micelles self-assembled by novel N-isopropylacrylamide oligomer grafted polyphosphazene

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Abstract

A novel thermosensitive amphiphilic copolymer of PNIPAm grafted polyphosphazene (PNIPAm-g-PPP) has been synthesized through a co-substitution reaction of poly-(dichlorophosphazene) with amino terminated NIPAm oligomer and glycine ethyl ester (GlyEt). The polymer obtained had a molar ratio of 1:5.25 PNIPAm to GlyEt and had a lower critical solution temperature (LCST) near 30 °C. The formation of polymeric micelles was confirmed by fluorescence, dynamic light scattering and transmission electron microscopy measurements.

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CITATION STYLE

APA

Zhang, J. X., Qiu, L. Y., Zhu, K. J., & Jin, Y. (2004). Thermosensitive micelles self-assembled by novel N-isopropylacrylamide oligomer grafted polyphosphazene. Macromolecular Rapid Communications, 25(17), 1563–1567. https://doi.org/10.1002/marc.200400180

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