Recurrence of chronic subdural hematoma due to low-grade infection

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Abstract

Despite the high incidence and multitudes of operative techniques, the risk factors for chronic subdural hematoma (CSDH) recurrence are still under debate and a universal consensus on the pathophysiology is lacking. We hypothesized that clinically inapparent, a low-grade infection could be responsible for CSDH recurrence. This investigation is a single-center prospective observational study including patients with recurrent CSDH. In total, 44 patients with CSDH recurrence received an intraoperative swab-based microbiological test. The intraoperative swab revealed an inapparent low-grade hematoma infection in 29% of the recurrent CSDH cases. The majority (69%) of the identified germs belonged to the staphylococcus genus. We therefore, propose a novel potential pathophysiology for CSDH recurrence.

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Dubinski, D., Won, S. Y., Trnovec, S., Gounko, K., Baumgarten, P., Warnke, P., … Sola, S. (2022). Recurrence of chronic subdural hematoma due to low-grade infection. Frontiers in Neurology, 13. https://doi.org/10.3389/fneur.2022.1012255

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