Electrophysiological Assessment of Spinal Cord Function on Rodents Using tcMMEP and SSEP

Abstract

Electrophysiological assays following experimental spinal cord injury objectively evaluate neurological function in the rodent. Major descending and ascending tracts can be monitored noninvasively using motor-evoked potentials and somatosensory-evoked potentials, respectively. This chapter summarizes the methods, procedures, and materials used to carry out these tests in our laboratory. Interpretation of results is also discussed.