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Voltage-Gated Sodium Channels as Drug Targets in Epilepsy-Related Sodium Channelopathies

  • Wengert E
  • Miralles R
  • Patel M
Springer International Publishing, (2024), 91-114
DOI: 10.1007/978-3-031-52197-3_4
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Abstract

Voltage-gated sodium channels (VGSCs) drive cellular excitability in various cells including the neurons of the central nervous system. Genetic variants in the genes encoding the brain-expressed VGSCs have been identified in patients with severe epilepsy syndromes...

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Wengert, E. R., Miralles, R. M., & Patel, M. K. (2024). Voltage-Gated Sodium Channels as Drug Targets in Epilepsy-Related Sodium Channelopathies. In Ion Channels as Targets in Drug Discovery (pp. 91–114). Springer International Publishing. https://doi.org/10.1007/978-3-031-52197-3_4

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