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Targeting Acid-Sensing Ion Channels in Disease

  • Senescall V
  • Budusan E
  • Knezic A
  • et al.
Springer International Publishing, (2024), 303-355
DOI: 10.1007/978-3-031-52197-3_10
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Abstract

Acidosis is a central feature of many pathological conditions, and while the activity of many ion channels is suppressed under acidic conditions, acid-sensing ion channels (ASICs) are exquisitely sensitive to decreases in pH and activated by protons. The expression...

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Senescall, V., Budusan, E., Knezic, A., Waqar, M., Butcher, N., Khan, N., … Rash, L. D. (2024). Targeting Acid-Sensing Ion Channels in Disease. In Ion Channels as Targets in Drug Discovery (pp. 303–355). Springer International Publishing. https://doi.org/10.1007/978-3-031-52197-3_10

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