Therapeutic results of different treatments for single hepatocellular carcinoma: A retrospective multicenter study (18 institutions)

Abstract

This retrospective study was undertaken to obtain information relevant to the therapeutic strategy and therapeutic results in single hepatocellular carcinoma. Eighteen institutions located mainly in the Kinki District of Japan took part in this study. The data of 3489 patients, who underwent different treatments between January 1, 1987 to March 31, 1998 were gathered and analyzed in this study. The results are shown follows. (The end-point of clinical observation was July 31, 1998) (1) Surgical resection was mainly performed for HCC of clinical stage I or II regardless of the tumor size. (2) The difference in survival of patients with HCC measuring 2.0 cm or less in diameter of clinical stage I or II between surgical resection and PEIT or PMCT was not statistically significant. (3) Among patients treated with PEIT, ten-year survivors were observed in patients with HCC measuring 3.0 cm or less in diameter. (4) In patients with HCC measuring more than 3.0 cm in diameter and of clinical stage I or II, survival rates of surgical resection were superior to those of other treatments except two groups (TAE+PEIT, 3