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A new homogeneity index based on statistical analysis of the dose-volume histogram

Journal of Applied Clinical Medical Physics (2007) 8(2) 9-17
DOI: 10.1120/jacmp.v8i2.2390
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Abstract

The goal of the present study was to develop a new dose-volume histogram (DVH)- based homogeneity index for effectively evaluating the dose homogeneity of intensity-modulated radiotherapy plans. The new index, called the sigma-index ("S-index") is defined as the standard deviation of the normalized differential DVH curve. In a study of 16 patients with brain tumors at our institution, the S-index was found to vary from 0.80 to 3.15. Our results showed that the S-index provides a more reliable and accurate measure of dose homogeneity than that given by conventional methods. A guideline for evaluating the dose homogeneity of treatment plans based on the S-index and its relation to equivalent uniform dose is discussed. © 2007 Am. Coll. Med. Phys.

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CITATION STYLE

APA

Yoon, M., Park, S. Y., Shin, D., Lee, S. B., Pyo, H. R., Kim, D. Y., & Cho, K. H. (2007). A new homogeneity index based on statistical analysis of the dose-volume histogram. Journal of Applied Clinical Medical Physics, 8(2), 9–17. https://doi.org/10.1120/jacmp.v8i2.2390

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