Towards a two-scale cellular automata model of tumour-induced angiogenesis

Abstract

This paper presents a new framework for modelling tumour-induced angiogenesis. Classical Cellular Automata approach is employed to model cellular and intracellular processes that occur in cancer tissue and neighbourhood. Vascular system is modelled by using Graph of Cellular Automata, which combines graph theory with Cellular Automata paradigm. A new model is proposed as a starting point for further investigations on multiscale model covering wide range of spatio-temporal scales including blood flow processes. The basis of the model with the algorithms are presented. Preliminary results with short discussion are also included. © Springer-Verlag Berlin Heidelberg 2006.