Donovanosis, Chancroid, and Endemic Treponematoses: Clinical Features and Control

Abstract

Until a few decades ago, chancroid, donovanosis, and endemic treponematoses were considered rare diseases, particularly in Western countries. In recent decades, the propensity to consider these diseases as rare has contributed to maintaining their status as neglected infections. However, these infections afflict large populations worldwide and several studies have demonstrated their biological synergisms with HIV disease both in terms of clinical interactions and that of enhanced transmission. A special attention has been given to better exploit their epidemiological, clinical, and treatment features also to enhance the skills of the clinicians to distinguish between these infections and the other better documented STI.