We report observations regarding the in vivo distribution of labelled kallikreins in plasma, liver and some other organs, twenty minutes following their intravenous injection in the rat. The kallikreins used were: tritiated homogeneous human plasma (HuPK) and horse urinary (HoUK) as well as highly purified iodinated rat plasma kallikrein (RPK). The main findings were: the liver cleared 15% of HuPK, 38% of RPK and 69% HoUK; with both types (plasma and tissue) of native kallikreins the liver was the main clearing organ.
CITATION STYLE
Borges, D., Sampaio, C., de la Llosa, P., & Prado, J. L. (1986). The liver is the main organ to clear plasma and tissue kallikreins from rat plasma, in vivo. Advances in Experimental Medicine and Biology, 198 Pt A, 229–233. https://doi.org/10.1007/978-1-4684-5143-6_31
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