Pregnancy: tolerance and suppression of immune responses.

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Abstract

Presence of foreign tissue in a host's body would immediately lead to a strong immune response directed to destroy the alloantigens present in fetus and placenta. However, during pregnancy, the semiallogeneic fetus is allowed to grow within the maternal uterus due to multiple mechanisms of immune tolerance, which are discussed in this chapter.

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Leber, A., Zenclussen, M. L., Teles, A., Brachwitz, N., Casalis, P., El-Mousleh, T., … Zenclussen, A. C. (2011). Pregnancy: tolerance and suppression of immune responses. Methods in Molecular Biology (Clifton, N.J.), 677, 397–417. https://doi.org/10.1007/978-1-60761-869-0_25

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