Abstract
The history of vaccination using live viruses extends through several centuries and is directly intertwined with the elimination of smallpox (variola major, Plotkin and Plotkin 2004). The word vaccine comes from the Latin “vaccinus” meaning “of cows”-an adjective joining variola (smallpox) and vaccinae to form cowpox (variola vaccinae, Jenner 1798; Riedel 2005) as distinct from the human disease (variola). Variola was easily transmitted, had high mortality, and for those who recovered, resulted in significant disfigurement due to scarring.
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CITATION STYLE
Galinski, M. S., Sra, K., Haynes, J. I., & Naspinski, J. (2015). Live attenuated viral vaccines. In Vaccine Analysis: Strategies, Principles, and Control (pp. 1–44). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-662-45024-6_1
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