Nonlinear Mixed Effects Models: Theory

  • Bonate P
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Abstract

This chapter introduces the theory behind nonlinear mixed effects models through the concept of a structural model or covariate model coupled to both fixed and random effects in a nonlinear manner. Modeling and estimation of model parameters in the face of different...

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Bonate, P. L. (2011). Nonlinear Mixed Effects Models: Theory. In Pharmacokinetic-Pharmacodynamic Modeling and Simulation (pp. 233–301). Springer US. https://doi.org/10.1007/978-1-4419-9485-1_7

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