Agreement and Precision of Deuterium Dilution for Total Body Water and Multicompartment Body Composition Assessment in Collegiate Athletes

12Citations
Citations of this article
21Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Background: Deuterium oxide (D2O) dilution is the criterion method for total body water (TBW) measurement, but results may vary depending on the specimen type, analysis method, and analyzing laboratory. Bioelectrical impedance (BIA) estimates TBW, but results may vary by device make and model. Objectives: We investigated the accuracy and precision of TBW estimates and how measurement conditions affected the accuracy of body composition using multicompartment body composition models. Methods: Eighty collegiate athletes received duplicate TBW measures acquired from 3 BIA devices (S10, SFB7, and SOZO) and from unique D2O combinations of specimen type (saliva, urine), analysis methodology [Fourier transform infrared spectrophotometry (FTIR), isotope-ratio mass spectrometry (IRMS)], and 3 different laboratories. TBW measures were substituted into 2-compartment (2C) and 5-compartment (5C) body composition models. Criterion measures were compared using Lin's concordance correlation coefficient cutoff of poor (<0.90), moderate (0.90–0.95), substantial (0.95–0.99), and almost perfect (>0.99). Results: Fifty-one participants (26 female) completed the protocol. Using IRMS saliva as the criterion TBW, all other measures produced a substantial or almost perfect agreement, except for SFB7 (poor) and SOZO (moderate). The 2C body composition measures using D2O and BIA produced poor agreement except for moderate agreement for lab 3 FTIR saliva. The 5C body composition measures using D2O produced a substantial agreement, whereas the BIA device S10 and SOZO had a moderate agreement, while the SFB7 had a poor agreement to the criterion. Test–retest precision varied between techniques from 0.3% to 1.2% for TBW. Conclusions: Small differences in TBW measurement led to significant differences in 2C models. The 5C models partially mitigate differences seen in 2C models when different TBW measures are used. Interchanging TBW measures in multicompartment models can be problematic and should be performed with these considerations.

References Powered by Scopus

User's guide to correlation coefficients

3475Citations
N/AReaders
Get full text

Bioelectrical impedance analysis - Part I: Review of principles and methods

2265Citations
N/AReaders
Get full text

Accurate assessment of precision errors: How to measure the reproducibility of bone densitometry techniques

1157Citations
N/AReaders
Get full text

Cited by Powered by Scopus

Maximal strength measurement: A critical evaluation of common methods—a narrative review

14Citations
N/AReaders
Get full text

Cardiovascular Function in Different Phases of the Menstrual Cycle in Healthy Women of Reproductive Age

7Citations
N/AReaders
Get full text

Development and validation of a rapid multicompartment body composition model using 3-dimensional optical imaging and bioelectrical impedance analysis

6Citations
N/AReaders
Get full text

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

Cataldi, D., Bennett, J. P., Quon, B. K., Liu, Y. E., Heymsfield, S. B., Kelly, T., & Shepherd, J. A. (2022). Agreement and Precision of Deuterium Dilution for Total Body Water and Multicompartment Body Composition Assessment in Collegiate Athletes. Journal of Nutrition, 152(9), 2048–2059. https://doi.org/10.1093/jn/nxac116

Readers' Seniority

Tooltip

PhD / Post grad / Masters / Doc 3

50%

Lecturer / Post doc 2

33%

Professor / Associate Prof. 1

17%

Readers' Discipline

Tooltip

Sports and Recreations 3

43%

Engineering 2

29%

Design 1

14%

Nursing and Health Professions 1

14%

Article Metrics

Tooltip
Mentions
References: 1

Save time finding and organizing research with Mendeley

Sign up for free