More than 50% of human tumours carry mutations in TP53, so strategies to restore the activity of this tumour suppressor in cancer cells are being actively investigated by drug companies. A team of researchers in Sweden and Russia now report the discovery of a compound that reactivates p53 function and induces apoptosis in human cancer cells.
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CITATION STYLE
Novak, K. (2002). p53 restoration. Nature Reviews Cancer, 2(3), 159–159. https://doi.org/10.1038/nrc771