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Spectrophotometric determination of chlorpheniramine maleate and phenylpropanolamine hydrochloride in dosage forms

  • Kaura A
  • Gupta V
  • Roy G
  • et al.
International Current Pharmaceutical Journal (2013) 2(5) 97-100
DOI: 10.3329/icpj.v2i5.14436
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Abstract

A rapid and simple method for simultaneous determination of Chlorpheniramine Maleate (CPM) and Phenylpropanolamine Hydrochloride (PPM) by first derivative UV spectrophotometry has been developed in combined pharmaceutical dosage forms. The proposed method was successfully applied for the determination of drugs in physical mixture and commercial formulations and results showed good linearity, precision and reproducibility. DOI: http://dx.doi.org/10.3329/icpj.v2i5.14436 International Current Pharmaceutical Journal, April 2013, 2(5): 97-100

Figures

  • Table 1: Statistical evaluation of linearity of standard solutions of PPM and CPM.
  • Table 2: (a) Statistical estimation of results of CPM and PPM in authentic, commercial and recovery studies samples (b) Variations in performed statistical analysis.
  • Figure 1: Normal and zero order overlain spectrum of CPM (1) and PPM (2).
  • Figure 2: First derivative overlain spectrum of CPM (1) and PPM (2).

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APA

Kaura, A., Gupta, V., Roy, G. S., & Kaura, M. (2013). Spectrophotometric determination of chlorpheniramine maleate and phenylpropanolamine hydrochloride in dosage forms. International Current Pharmaceutical Journal, 2(5), 97–100. https://doi.org/10.3329/icpj.v2i5.14436

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