Abstract
The authors’ analysis of literature sources provided evidence that the main candidates for the role of end effector of ischemic preconditioning of the heart are: MPT pores (mitochondrial permeability transition pores), nexuses, and the cytoskeleton. Almost all known intracellular signal cascades ultimately converge on MPT pores, cytoskeletal components, and nexuses.
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Tsibul’nikov, S. Y., Maslov, L. N., Tsepokina, A. V., Khutornaya, M. V., Kutikhin, A. G., Tsibul’nikova, M. R., & Nam, I. F. (2017). The question of the end effector of ischemic preconditioning of the heart. Neuroscience and Behavioral Physiology, 47(6), 681–689. https://doi.org/10.1007/s11055-017-0455-6
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