Therapeutic Aspects of Polycystic Ovary Syndrome in Adolescence

Abstract

Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism, chronic anovulation, and insulin resistance. The syndrome manifests with hirsutism, irregular menses, infertility, dyslipidemia, as well as a higher risk for type 2 diabetes mellitus, and cardiovascular disease. PCOS has a pubertal onset. The clinical signs and neuroendocrine features of adolescents with PCOS resemble those found in adult women with the syndrome. Early recognition and prompt treatment in adolescents is essential for preventing long-term consequences. This chapter reviews the clinical, hormonal, and metabolic features of PCOS in adolescence and current treatment options.