These drugs contain steroid glycosides which specifically affect the dynamics and rhythm of the insufficient heart muscle.The steroids are structurally derived from the tetracyclic 10,13-dimethyl-cyclopentanoperhydrophenanthrene ring system. They possess a γ\_lactone ring (cardenolides) or a δ-lactone ring (bufadienolides) attached in the β-position at C-17. The typical sugar residues are derived from deoxy and/or C-3-O-methylated sugars, and they are linked glycosidically via the C-3-{OH} group of the steroid skeleton.
CITATION STYLE
Wagner, H., & Bladt, S. (1996). Cardiac Glycoside Drugs. In Plant Drug Analysis (pp. 99–123). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-00574-9_5
Mendeley helps you to discover research relevant for your work.