Taking whispering gallery mode biosensing to the single protein limit

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Abstract

Finding a method for label-free sensing of individual protein is considered the "Holy Grail" in the bio-sensing field. An ideal technology that could do this would be able to follow the sensing of biological antigen-antibody interactions in their native form and in real-time without interfering tags. The challenge is great, however the rewards are likely greater. To date the most sensitive photonic label-free transducer is a resonant biosensor in the form of a Ring Resonator or Whispering Gallery Mode (WGM) resonator for which there have been a number of recent reviews [1, 2]. © 2013 Springer Science+Business Media Dordrecht.

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Arnold, S., Dantham, V. R., Rivilis, N., & Holler, S. (2013). Taking whispering gallery mode biosensing to the single protein limit. In NATO Science for Peace and Security Series B: Physics and Biophysics (pp. 271–285). Springer Verlag. https://doi.org/10.1007/978-94-007-5313-6_12

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