Next-Generation Sequence Assemblers

Abstract

There are several assemblers employed in next-generation environment. These may be classified according to their respective graph construction approaches (see Chap. 9) or their targeted data sets. In this chapter, we will present select examples of next-generation sequence assemblers and discuss their implementation approaches. The assemblers we discuss have been selected carefully to represent the available assembly approaches and the first four stages of the assembly process. Tools related to assembly assessment, the fifth stage, have been previously discussed in Chap. 10.