24-O-ethylmanoalide, a manoalide-related sesterterpene from the marine sponge Luffariella cf. variabilis

Abstract

A new manoalide-related sesterterpene, 24-O-ethylmanoalide (3), was isolated from the Indian Ocean sponge Luffariella cf. variabilis, together with the known compounds manoalide (1), seco-manoalide, manoalide monoacetate and 24-O-methylmanoalide (2). The structure of compound 3 was elucidated by interpretation of its spectroscopic data. © 2008 by the authors; licensee Molecular Diversity Preservation International.