T-cell clones can frequently be identified in peripheral blood. It can be difficult to appreciate whether these are benign and transient or whether they signify a clonal disorder. We review factors that aid in understanding the relevance of T-cell clones. Conversely, obvious pathological T-cell clones can be detected in blood, but there is uncertainty in how to categorize this clonal T cell population, thus, we adopt a multidisciplinary review of the clinical features, diagnostic material and radiology before making the diagnosis. In this review we shall discuss some of these challenges faced when diagnosing mature T-cell leukemias.
CITATION STYLE
El-Sharkawi, D., Attygalle, A., & Dearden, C. (2022, March 9). Mature T-Cell leukemias: Challenges in Diagnosis. Frontiers in Oncology. Frontiers Media S.A. https://doi.org/10.3389/fonc.2022.777066
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