Squamous cell carcinoma of the anal margin with pruritus ani of long duration

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Abstract

BACKGROUND. Anal margin is an unusual location for squamous cell carcinoma (SCC). On rare occasions, anal margin carcinoma is the cause of pruritus ani. OBJECTIVE. To describe a case of SCC of the anal margin with pruritus ani of long duration. RESULTS. A 52-year-old man had been aware of perianal itching for over 10 years. Examination of the perianal area revealed a reddish, eroded, hard nodule that was 2.0 × 1.5 × 0.3 cm in size located in the 3 o'clock position. The histopathologic diagnosis was well-differentiated SCC. The nodule was totally excised with a 1-cm margin. No recurrence or metastases were observed for 7 months. CONCLUSION. When pruritus ani does not respond to conservative therapy and when symptoms have existed for a long time, we should suspect the presence of malignancy.

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APA

Handa, Y., Watanabe, O., Adachi, A., & Yamanaka, N. (2003). Squamous cell carcinoma of the anal margin with pruritus ani of long duration. Dermatologic Surgery, 29(1), 108–110. https://doi.org/10.1046/j.1524-4725.2003.29003.x

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