Quantify Physiologic Interactions Using Network Analysis

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Abstract

To better understand the neural interactions amongst human organ systems, this work provides a framework of data analysis to quantify forms of neural signalling. We explore network interactions among the human brain and motor controlling. The main objective of this work is to provoke unique challenges in the emerging Network Physiology field. The proposed method applies network analysis techniques including power coherence for connectivity discovering and correlation measurement for profiling relationships. We used a well-designed dataset of 50 subjects over 14 different scenarios for each individual. We found network models for these interactions and observed informative network behaviours. The information can be used to study impaired communications that can lead to dysfunction of organs or the entire system such as sepsis.

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Pham, T. T., & Dutkiewicz, E. (2019). Quantify Physiologic Interactions Using Network Analysis. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 11619 LNCS, pp. 142–151). Springer Verlag. https://doi.org/10.1007/978-3-030-24289-3_12

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