This paper presents results for dispensing living cells using a pneumatic dispensing system to verify the feasibility of using this system to fabricate biomaterials. Living cells (i.e., mouse 3T3-J2 fibroblast) were dispensed with different dispensing pressures in order to evaluate the effect of dispensing process on cell viability and proliferation. Based on the results of a live-dead assay, more than 80% of cell viability has been confirmed which was reasonably similar to that in the control group. Furthermore, measurement of cell metabolic activity after dispensing confirmed that the dispensed cell proliferated at a rate comparable to that of the control group. These results demonstrate that the pneumatic dispensing system is a promising tool for fabrication of biomaterials.
CITATION STYLE
Lee, S., Kim, H., & Kim, J. (2017). Feasibility study of a biocompatible pneumatic dispensing system using mouse 3T3-J2 fibroblasts. Micro and Nano Systems Letters, 5(1). https://doi.org/10.1186/s40486-017-0061-y
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