Repurposing of Flavonoids as Promising Phytochemicals for the Treatment of Lung Carcinoma

Abstract

Flavonoids are the polyphenolic secondary metabolites that were obtained from the plants. In recent years, the study and research of flavonoids have become important due to new findings about their diverse pharmacological actions. Here in this chapter, we described about the repurposed use of flavonoids to treat different types of lung cancers such as small-cell lung cancer and non–small-cell lung cancer. The flavonoids covered in this chapter are vital in terms of their role and mechanism of action to hit many targets linked with lung cancer. Further this chapter includes repurposing, structural modification, as well as an in-depth understanding of the various functional groups present in flavonoids and their impact on the biological mechanism to develop some improved therapeutic strategies for the prevention and treatment of lung carcinomas. The repurposing of flavonoids provides a fruitful alternative against the toxic chemotherapy treatments for the various types of cancer and diseases.