Clinical management of elderly patients' metastatic prostate cancer: Other treatments and supportive care

Abstract

Prostate cancer is a frequent disease, especially in elderly men. Treatment of metastatic prostate cancer is palliative at any age. It requires a global oncological approach with the input of several teams: urologists, medical oncologists, radiotherapists, other surgeons etc. Hormone deprivation is the main treatment for hormone-sensitive metastatic disease. Chemotherapy is the standard treatment for metastatic castration-resistant disease, but new drugs, mainly new hormonal treatments, are being developed. Other treatment modalities can be used to treat patients in these situations, such as bone-targeted agents, radiopharmaceutics etc. Evolution of the disease is variable, but some problems, such as pain, fractures, compressions, etc., occur frequently and need a specific approach.