Effect of skull type on the relative size of cerebral cortex and lateral ventricles in dogs

14Citations
Citations of this article
60Readers
Mendeley users who have this article in their library.

Abstract

Volume measurements of the brain are of interest in the diagnosis of brain pathology. This is particularly so in the investigation hydrocephalus and canine cognitive dysfunction (CCD), both of which result in thinning of the cerebral cortex and enlarged ventricles. Volume assessment can be made using computed tomography or more usually magnetic resonance imaging (MRI). There is, however, some uncertainty in the interpretation of such volume data due to the great variation in skull size and shape seen in dog. In this retrospective study, we examined normal MRI images from 63 dogs < 6 years of age. We used a continuous variable, the cranial index (CrI) to indicate skull shape and compared it with MRI volume measurements derived using Cavalieri's principle. We found a negative correlation between CrI and the ratio of cortical to ventricular volume. Breeds with a high CrI (large laterolateral compared to rostrocaudal cranial cavity dimension) had a smaller ratio of cortical to ventricular volume (low C:V ratio) than breeds with lower CrI skull types. It is important to consider this effect of skull shape on the relative volume estimates of the cerebral cortex and ventricles when trying to establish if pathology is present.

References Powered by Scopus

NIH Image to ImageJ: 25 years of image analysis

47057Citations
N/AReaders
Get full text

OsiriX: An open-source software for navigating in multidimensional DICOM images

1554Citations
N/AReaders
Get full text

The efficiency of systematic sampling in stereology - Reconsidered

1190Citations
N/AReaders
Get full text

Cited by Powered by Scopus

Significant neuroanatomical variation among domestic dog breeds

71Citations
N/AReaders
Get full text

Morphogenesis of Canine Chiari Malformation and Secondary Syringomyelia: Disorders of Cerebrospinal Fluid Circulation

33Citations
N/AReaders
Get full text

Novel contributions in canine craniometry: Anatomic and radiographic measurements in newborn puppies

13Citations
N/AReaders
Get full text

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

Pilegaard, A. M., Berendt, M., Holst, P., Møller, A., & McEvoy, F. J. (2017). Effect of skull type on the relative size of cerebral cortex and lateral ventricles in dogs. Frontiers in Veterinary Science, 4(MAR). https://doi.org/10.3389/fvets.2017.00030

Readers' Seniority

Tooltip

PhD / Post grad / Masters / Doc 20

61%

Researcher 6

18%

Professor / Associate Prof. 4

12%

Lecturer / Post doc 3

9%

Readers' Discipline

Tooltip

Veterinary Science and Veterinary Medic... 26

65%

Medicine and Dentistry 7

18%

Agricultural and Biological Sciences 6

15%

Neuroscience 1

3%

Article Metrics

Tooltip
Social Media
Shares, Likes & Comments: 2

Save time finding and organizing research with Mendeley

Sign up for free