Perfluorinated Solvents — a Novel Reaction Medium in Organic Chemistry

Abstract

Although perfluorinated hydrocarbons are well known, they have only recently found application in organic chemistry as a useful class of solvents. Their physical properties make them unique for their use as reaction media. Since perfluorocarbons are immiscible with many common organic solvents, they are suitable for the formation of biphasic systems. This overview describes the utilization of perfluorocarbons as reaction media for various kinds of reaction such as oxidation, bromination, etc. In addition, a novel biphase reaction system based on perfluorinated solvents as well as its application in organic synthesis is presented.