In vitro anti-arthritic activity

Abstract

Formaldehyde-induced arthritis and complete Freund’s adjuvant (CFA)- induced arthritis in rats are well-known models to determine the anti-arthritic activity. Arthritis is a symptom of chronic inflammation. It is a chronic progressive disorder, developing over months or years and involving essentially the synovial joints of the body. Hence, these two models become the basis of this chapter to analyse the anti-arthritic activity.