Preparation of Ultra Fine Emulsion by Phase Inversion Temperature(PIT) Emulsification.

Abstract

Phase inversion temperature (PIT) emulsification is the method which use the change of the balance for hydrophilic-hydrophobic of nonionic surface active agent. In this study emulsions were assembled according to PIT emulsification with POE (n) sorbitol tetraoleate (n: 30, 60) and POE (20) hydogenated castor oil as emul sifier, and were subjected to evaluation of particle size and storage stability. Thus in order to obtain ultra fine emulsion with less than 200nm in diameter, the combination of emulsifier and oil is important. Stability of ul tra fine emulsion prepared with POE (20) hydogenated castor oil were good, on the other hand prepared with POE (n) solbitol tetraoleate (n: 30, 60) were depended on oils. We could obtain ultra fine and stable emulsion with mixture of the emulsifiers for various oils.