Types of nanozymes can produce free radicals and/or reactive oxygen species (ROS) to serve as broad spectrum antibacterial materials. Developing nanozyme-based antibacterial materials with good biocompatibility exhibits promising application prospects. In this study, we doped Mo to ZIF-8 (both components have good biocompatibility) to prepare a new nanozyme, Mo@ZIF-8, which can produce hydroxyl radicals (•OH) triggered by a low dosage of hydrogen peroxide (H2O2), exhibiting effective antibacterial capability against both Gram-negative bacteria (Escherichia coli) and Gram-positive bacteria (Staphylococcus aureus). This work provides a reference for the design of antibacterial nanozymes with good biocompatibility.
CITATION STYLE
Lian, Z., Lu, C., Zhu, J., Zhang, X., Wu, T., Xiong, Y., … Yang, R. (2022). Mo@ZIF-8 nanozyme preparation and its antibacterial property evaluation. Frontiers in Chemistry, 10. https://doi.org/10.3389/fchem.2022.1093073
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