Introduction

Abstract

Schizophrenia is a heterogeneous disorder which typically afflicts younger individuals, often leading to lifelong disability. The most dramatic aspect of this disease is the periodic episodes of psychotic symptoms (e.g., auditory hallucinations, paranoid delusions) which at times require emergent interventions to protect the individual and others. This illness, however, also includes more persistent impairment in multiple areas of cognition, substantial deficits in interpersonal relationships, and depressed mood, at times predisposing individuals to a heightened risk of suicide. The culmination of these symptoms may be a marked diminution in the ability to function adequately (e.g., socially, occupationally), as well as a greatly diminished quality of life. This book provides the reader with information about the need for and components of a comprehensive strategy to help patients; the optimal use of existing biological and psychosocial therapies; the use of novel treatments based on positive preliminary efficacy, safety, and tolerability findings; and future directions in addressing the diagnosis, pathophysiology, and management of schizophrenia. The goal is to review the most promising areas of research into this disorder and translate their findings into practical recommendations for improving the lives of patients who suffer from schizophrenia.