Therapeutic potential of resveratrol: The in vivo evidence

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Abstract

Resveratrol, a constituent of red wine, has long been suspected to have cardioprotective effects. Interest in this compound has been renewed in recent years, first from its identification as a chemopreventive agent for skin cancer, and subsequently from reports that it activates sirtuin deacetylases and extends the lifespans of lower organisms. Despite scepticism concerning its bioavailability, a growing body of in vivo evidence indicates that resveratrol has protective effects in rodent models of stress and disease. Here, we provide a comprehensive and critical review of the in vivo data on resveratrol, and consider its potential as a therapeutic for humans.

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APA

Baur, J. A., & Sinclair, D. A. (2006, June). Therapeutic potential of resveratrol: The in vivo evidence. Nature Reviews Drug Discovery. https://doi.org/10.1038/nrd2060

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