This chapter describes the methods that can be applied to successfully freeze-dry proteins. Laboratory applications are given at small scale, typified by the purification of a protein intermediate as part of the analytical characterization of a protein, and at intermediate scale, as illustrated by the pilot development of a lyophilized protein reference material such as for use in bioassay or immunoassay. Advice on common problems with freeze-drying of proteins is also given.
CITATION STYLE
Matejtschuk, P. (2007). Lyophilization of proteins. Methods in Molecular Biology (Clifton, N.J.). https://doi.org/10.1007/978-1-59745-362-2_4
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