Bacteriophage libraries containing millions of variants of phage tail fiber motifs on a common structural scaffold give rise to infectious phages with expanded or altered host ranges, which may be useful for phage therapy efforts.
CITATION STYLE
Yehl, K., Lemire, S., Yang, A. C., Ando, H., Mimee, M., Torres, M. D. T., … Lu, T. K. (2019). Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis. Cell, 179(2), 459-469.e9. https://doi.org/10.1016/j.cell.2019.09.015
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