Menopause

Abstract

Menopause is defined as the cessation of menstrual periods occurring from the genetically programmed loss of ovarian follicles. The transition between the woman’s fertile period and menopause begins with variations in the duration of menstrual cycle and an increase in serum concentrations of follicle-stimulating hormone (FSH) and ends with the final menstrual cycle, unrecognized until 12 months of amenorrhea is completed. This chapter reviews the epidemiological aspects, clinical manifestations, diagnosis, differential diagnosis, current treatment, and new perspectives in the treatment of the menopause.