Computer Modeling of Electrochemical Impedance Spectra for Defected Phospholipid Membranes: Finite Element Analysis

Abstract

This study deals with application of finite element method to model electrochemical impedance spectra of phospholipid membranes containing defects. Practical issues of choosing mesh and solver parameters are investigated in order to obtain the best combination of solution accuracy and computation times for the given problem. A simple mesh generation strategy suitable for membrane models with various randomly generated defect distributions is presented. Models with varying mesh densities were solved with direct and iterative solvers and solution accuracy was evaluated in terms of EIS spectral features. Computation times of models with various mesh sizes and solver configurations were also measured in two different computing environments.