Renal denervation is being used as a blood pressure lowering therapy for patients with apparent treatment resistant hypertension. However, this population does not represent a distinct disease condition in which benefit is predictable. In fact, the wide range in effectiveness of renal denervation could be a consequence of this heterogeneous pathogenesis of hypertension. Since renal denervation aims at disrupting sympathetic nerves surrounding the renal arteries, it seems obvious to focus on patients with increased afferent and/or efferent renal sympathetic nerve activity. In this review will be argued, from both a pathophysiological and a clinical point of view, that chronic kidney disease is particularly suited to renal denervation.
CITATION STYLE
Sanders, M. F., & Blankestijn, P. J. (2016, June 8). Chronic kidney disease as a potential indication for renal denervation. Frontiers in Physiology. Frontiers Research Foundation. https://doi.org/10.3389/fphys.2016.00220
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